Cleanrooms play an inherent role in pharmaceutical, food production, research units, and other manufacturing facilities that should avoid pathogens. A cleanroom design ensures to filter of pollutants and offers the cleanest area possible for operations. Apart from avoiding pathogens, cleanrooms also control other variables such as airflow, temperature, and humidity.
Cleanrooms have HEPA and ULPA filters to terminate the pathogens from the outside ambient air. The filtered air will then be sent into the controlled environment, flushing out the contaminants from the internal activities. The filters will recirculate the contaminated air to the ambient air. There are many different types of cleanrooms available. The right type of cleanroom design depends on the application and size requirement.
Cleanroom design and construction requirements
Cleanrooms are technically high-risk areas. They have to be treated with complete attention as the contaminants could be a great threat to people and product quality. To minimize the risks of contamination, it is mandatory to monitor and control pathogens at all times. Cleanroom design should ensure that all relevant parameters, such as humidity, temperature, and airborne particles, are under check. The cleanroom construction requirements are as follows.
- Measure and control the cleanroom environment precisely
- Check the airflow volume, pressure differences, and particle concentration.
- It is also important to monitor the environmental emissions in the cleanroom.
- It is mandatory to incorporate early fire detection methods, explosion protection systems, and guided operation and evacuation in the cleanroom designs.
- Cleanroom construction should follow good manufacturing practices along with the verification of all parameters relevant to quality and infrastructure.
Applications of cleanrooms:
Cleanrooms find extensive applications in diverse industries. A simple rule is that any manufacturing facility that requires that the manufacturing process shouldn’t be affected by air particles and contaminants require a cleanroom. Some common industries that need cleanrooms are,
- Research units
- Manufacturing units
- Pharmaceutical companies
- Drug research laboratories
- Industries that manufacture electronic components
- Aerospace manufacturing units.
- Nanotechnology production units
- Military applications
- Optics and lens manufacturing units.
FAQ: What are the requirements for Pharmaceutical cleanroom design and construction?
The pharmaceutical cleanroom design and construction are expected to abide by a set of strict rules and requirements. The basic norm for constructing a pharmaceutical cleanroom is that it should have 240 to 600 air changes in an hour and 35 to 70% roof inclusion. This helps to enhance the interior climate of about 0.1μm particles/cu.m of space.
How to choose the best partner for cleanroom design and construction?
Cleanrooms are generally a building that exists within another building. They are mandatory to have a controlled environment. They should have separate systems for heating, air conditioning, flooring, lighting, and ventilation. There should be no exterior walls in the cleanroom design. They should not have direct outside access as well.
While planning the cleanroom construction, it is mandatory to make sure that it has differential pressure with respect to the building interiors. It is mandatory to maintain this pressure difference at all times to mitigate particle infiltration from a clean space.
The first step in planning the cleanroom construction is to create the utility matrix. This will outline the specifications of every of equipment in the cleanroom. The matrix should have approval from the authorities with the participation of the cleanroom operators. With the help of the user matrix, the other support systems will be planned for the cleanroom.
Cleanroom construction is challenging and demands extensive attention in both its design and construction. The best cleanroom design and construction services will follow industry standards and make use of the matrix as their blueprint. They will work in close liaison with the operator of the cleanroom and make sure it matches the needs of the end users. The construction service will also ensure to achieve the best ROI for the operating space.
A clean room is a room that has control over the concentration of airborne particles. The main intention of having a clean room is to mitigate the introduction and retention of particles inside the room with respect to pressure, temperature, and humidity. The best cleanroom design service providers will offer turnkey solutions for cleanroom installation. Their turnkey cleanroom construction services will help companies navigate the complex construction process and achieve success in cleanroom design and construction.